Cancers MDPI

📢 Cancers MDPI was awarded an updated Impact Factor of 4.5 in the 2023 Journal Citation Reports released by Clarivate in June 2024. The journal rank has now been upgraded to JCR Q1 (78/322 in the 'Oncology' category, 5-Year Impact Factor: 4.9). 👉 Read more: https://lnkd.in/g7JUNySw

📢Today we share the #Article "Histology and PSMA Expression on Immunohistochemistry in High-Risk Prostate Cancer Patients: Comparison with 68Ga-PSMA PET/CT Features in Primary Staging" 🤝by luigia vetrone et al. Alma Mater Studiorum – Università di Bologna Access the full paper here↘️ https://lnkd.in/d3RYPt7N Keywords: PET-parameters; PSMA-immunochemistry; prostate cancer

🧐Check out the #Article "Novel Agents as Main Drivers for Continued Improvement in Survival in Multiple #Myeloma" 👏by Borja Puertas et al. 🔗Find the full paper here: https://lnkd.in/dDK8__K5 Keywords: novel agents; survival; long survivors

🔊Happy to share the Special Issue "The Role of Regucalcin in Cancer" edited by Prof. Dr. Masayoshi Yamaguchi (University of Hawaii at Manoa)👏 ⏰Deadline for manuscript submissions: 1 March 2025. Find more details here: https://lnkd.in/dmaRvfe6 keywords: cancer suppressor protein; cell signaling; metabolic regulation; transcription factor; cell proliferation; cell death; drug development; cancer therapy

💬We share the #Article "Detection Efficacy of 68Ga-PSMA-11 PET/CT in Biochemical Recurrence of Prostate Cancer with Very Low PSA Levels: A 7-Year, Two-Center “Real-World” Experience" 👥by Caroline Burgard et al. Access the full paper here👉 https://lnkd.in/dnAdYdUz Keywords: prostate cancer; biochemical recurrence; low serum prostate-specific antigen (PSA) concentration

🎖️Check out the Editor's Choice #Review "Variant Allele Frequency Analysis of Circulating Tumor DNA as a Promising Tool in Assessing the Effectiveness of Treatment in Non-Small Cell Lung Carcinoma Patients" 💬by Natalia Galant et al. Medical University of Lublin 📌Link here: https://lnkd.in/djHTBNzW 🔹Lung cancer remains a leading cause of death among cancer patients, and new tools like variant allele frequency (VAF) analysis are being investigated to guide therapy, especially for non-small cell lung cancer (NSCLC). VAF, measured using NGS or PCR from tissue samples or circulating tumor DNA (ctDNA) in liquid biopsies, shows promise for monitoring therapy due to its non-invasive nature and ability to frequently collect material. Although VAF analysis is useful for tracking tumor progression and making treatment decisions, several challenges need to be addressed before it can be routinely implemented in clinical practice, as discussed in this interesting review.🔹

🔊Today we share the #Review "Recent Advances in Cervical Cancer Management: A Review on Novel Prognostic Factors in Primary and Recurrent Tumors" 🧐by Angela Santoro et al. Fondazione Policlinico Universitario Agostino Gemelli IRCCS Find the full paper here⏩ https://lnkd.in/dVy_auyQ Keywords: cervical cancer; prognosis; grading

🔊We share the Special Issue "Detection of Breast Cancer with Mammography" edited by Dr. Luca Nicosia (IEO Istituto Europeo di Oncologia)❕ 💬Deadline for manuscript submissions: 15 April 2025. Find more details here⏩ https://lnkd.in/dtBNHgYY

🎖️Check out the Editor's Choice #Article "Molecular, Metabolic, and Subcellular Mapping of the Tumor Immune Microenvironment via 3D Targeted and Non-Targeted Multiplex Multi-Omics Analyses" 👏by Sammy Ferri-Borgogno et al. MD Anderson Cancer Center 📎Link here: https://lnkd.in/gK3rRkDK 🔹Most platforms for reconstructing the tumor-immune microenvironment (TIME) of solid tumors lack the ability to explore the 3D spatial context at a single-cell resolution, missing critical cell–cell and cell–extracellular matrix interactions. To address this, the authors developed a new pipeline integrating multiplex spatially resolved multi-omics platforms to identify signaling networks among various cell types and the ECM in the 3D TIME of gynecologic tumor samples. This pipeline, combining mass spectrometry imaging, spatial transcriptomics, and targeted proteomics, produced spatially resolved 3D maps at single-cell resolution, revealing cellular neighborhoods and providing insights for predictive biomarkers and therapeutic targets to improve patient outcomes.🔹

📣Today we share the #Review "Multifactorial Diseases of the Heart, Kidneys, Lungs, and Liver and Incident Cancer: Epidemiology and Shared Mechanisms" 🧐by Canxia Shi et al. University of Groningen Find the full paper here▶ https://lnkd.in/dpsWRWb8 Keywords: incident cancer; onco-nephrology; chronic obstructive pulmonary disease;